Nandrolone Decanoate: Use, Abuse and Side Effects

Nandrolone Decanoate: Use, Abuse and Side Effects

There is no time that the body will hurt and ache like it will during a cutting phase and Nandrolone is a great remedy. But others will use it as a direct steroid protectant, something to help protect lean tissue that would otherwise be lost due to the necessary caloric restrictions. It’s not uncommon to see a bodybuilder use Nandrolone during the first half of his contest prep and then drop it the second half for steroids that are better suited to hardening, although he may leave in a small amount all the way to the end for therapeutic benefit. Nandrolone (all forms) is a 19-nortestosterone (19-nor) anabolic androgenic steroid. The 19-nor distinction notes a structural change to the testosterone hormone, specifically the testosterone hormone lacking the carbon atom at the 19th position. It is this slight alteration that gives us Nandrolone; Testosterone, remove the 19th carbon and a new steroid is born.

What are the Metabolic Effects of Nandrolone?

An earlier 2010 study by Papaspiliopoulos et al. (32) examined 48 male rabbits that underwent rotator cuff incision and reconstruction after stratification into groups based on local nandrolone administration and immobilization. In this study, local administration of nandrolone proved detrimental to wound healing however, systemic administration was not studied (32). Other limitations include the fact that anabolic steroids affect the tensile strength of tendons that may then cause failure with less elongation (33). Local administration of nandrolone may impair the healing of acute tendon injuries and the perceived benefits to retracted muscle may be outweighed by its effects on tendon healing (34).

• The primary cardiovascular side effects of Nandrolone surround cholesterol, especially the reduction of HDL cholesterol (good cholesterol).
• Only nandrolone and a few of its derivatives like normethandrone and norethandrolone have this very special property.
• There were an insignificant number of published quality data available for meta-analysis, so a systematic review was performed.
• Believe it or not, Nandrolone isn’t very estrogenic, it is possible to experience estrogen-like side effects because of using it.
• The common idea is that Nandrolone is a great bulking steroid and the truth is it is a fantastic bulking steroid.

It should also be noted that if you use something like Finasteride to try and reduce the side effects, it’s not going to do much. Just like with estrogen and Nandrolone, using a 5-alpha reductase inhibitor like Finasteride is just Stanos (Stanozolol) 10 mg Elbrus Pharmaceuticals buy online going to exacerbate non-existent androgenic symptoms by making the compound as a whole much more androgenic. Though it will work on testosterone based steroids you’re using with Nandrolone. When trying to deal with those estrogenic effects of Nandrolone, you can do it by using any form of anti-estrogen that you prefer. The best kinds are those that are considered Aromatase Inhibitors (AIs) like an Arimidex, which is the brand for the compound Anastrozole. You can also use a Selective Estrogen Receptor Modulator (SERM) like Tomoxifen, typically known in the bodybuilding circles as Nolvadex.

Dosage et administration

For someone that is just using it for performance enhancement, like aesthetic weight lifters or competitive athletes, they really love it, but the truth is, many of these individuals don’t truly understand why they like the drug so much. In other words, they don’t know much about the science behind it and proclaim a lot of benefits that might not really be there. Most people assume Nandrolone is great for bulking, and in truth, it is really great for bulking. And frankly, that’s disappointing to not maximize everything this steroid is capable of doing. With something as versatile and incredible as Nandrolone, it’s doing a disservice to the compound. For one, you have to understand that the quality of the compound is not solely based on the amount of mass it can put on your body.

The reduced androgenic impact of nandrolone in skin and hair follicles relative to testosterone make it a favorable potential alternative option for androgen therapy both for transfeminine people and for some transmasculine people. An anabolic steroid that has been investigated to some degree in the treatment of male health is 19-nortestosterone (or nandrolone, deca-durabolin). This synthetic anabolic steroid has been available for decades and has been studied in multiple clinical pathologies. Early investigations of nandrolone focused on its potential uses in the treatment of osteoporosis.

Availability, Legality and Buying Nandrolone Online:

As a result, ND had been implicated in doping, until its health risks became evident and the International Olympic Committee (IOC) abolished the use of ND in sports competitions 38. While it is more common among so-called gym visitors, this substance is also used in criminal circles and in competitive situations where personal aggressiveness could be a determining factor. Endocrine, cardiovascular, skin and psychiatric disorders are the most reported. As 5α-reductase may not be critical for penile enlargement at puberty, nandrolone may allow for no less bottom growth (clitoral enlargement) in transmasculine people than does testosterone. Indeed, nandrolone has been reported to produce clitoral enlargement as a side effect in women and penile growth in prepubertal boys (Camerino & Sala, 1960; Camerino & Sciaky, 1975).

In a study by Clark and colleagues, the authors reported a case of a subject using several drugs, thus causing dilated cardiomyopathy 76. Almaiman and colleagues showed an increase in creatine kinase (CKL) and creatine kinase muscle and brain subunits (CK-MB) 30. In a case reported by Huie and coworkers, an acute myocardial infarction in an anabolic steroid user, raised questions about any link between them 75. Steroids help healing, in part, because they lessen the activity of the immune system. Your body fights infection and germs with white blood cells and other chemicals that can lead to inflammation. By reducing this immune activity, steroids can lessen inflammation and tissue damage, as well.

It’s also a good idea to keep an eye on your cholesterol levels during and post use to ensure your good state of health. Interestingly, Internet and discussion group anecdotal data suggests that nandrolone is effective in decreasing joint pain in bodybuilders. These athletes lift large amounts of weights putting extreme pressure on their joints while reporting improvement and lowered pain with the use of nandrolone. While limited data is available, and dosages are unknown, further investigations are needed to determine the effects of nandrolone on joints in general, and the rotator cuff in particular.

Several molecular pathways are implied in androgen-induced cardiac damage, where nuclear and cytoplasmatic factors play a role 77. ND abnormally affects ionic balance in several ways, including altered Ca2+ mobilization 74 downregulated K+ channel-interacting proteins causing longer QT repolarization time 78, along with increased oxidative stress and pro-apoptotic effects 79. Most AAS abusers tend to use multiple substances at once, causing synergic effects and systemic disorders whose causes cannot be quickly identified by physicians.

In published photographs of individuals with the condition however, features like lack of body hair and rounded feminine hairlines can be noted. Nandrolone is a synthetic anabolic steroid that possesses unique qualities and is potentially beneficial in the treatment of male health alone, or as an adjunct to TST for hypogonadal men. Nandrolone has a relatively long half-life in the plasma and a strong binding affinity for androgen receptors. The lack of conversion to DHT could mean decreased hair loss in men undergoing TST suggesting a novel use for this medication in a subpopulation of hypogonadal men. Nandrolone preferentially stimulates growth of skeletal muscle and lean body mass that may provide benefit in reducing components of metabolic syndrome. Moreover, preliminary work on nandrolone has suggested a potential role in the treatment of joint healing, particularly in rotator cuff injuries.